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Cyclosporine resistant effector cells in rabbit skin allografts
Authors:A Gratwohl  I Riederer  K Walstra  H Baldomero  B Speck
Institution:(1) Division of Hematology, Department of Research, Kantonsspital, CH-4031 Basel, (Switzerland)
Abstract:Summary Histoincompatible skin grafts in rabbits treated with cyclosporine can permanently engraft but show a transient mononuclear cellular infiltrate. This transient cyclosporine-resistant infiltrate consists of cells which are sensitive to steroids, radiation and cryopreservation. They have the same ACM-1 phenotype and the same characteristics as cyclosporine-sensitive cells.9 January 1987Supported by the Swiss National Research Foundation, Grant No. 3.908-0.83.
Keywords:Cyclosporine  skin transplantation  bone marrow transplantation  rabbit  graft-versus-host-disease
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