| 复方红花降压胶囊的降脂作用及安全性动物实验研究 |
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| 引用本文： | 徐彩云,张大维,邴国强,李鑫月,吴凌宇.复方红花降压胶囊的降脂作用及安全性动物实验研究[J].实验动物科学,2010,27(5):29-32. |
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| 作者姓名： | 徐彩云 张大维 邴国强 李鑫月 吴凌宇 |
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| 作者单位： | [1]吉林大学白求恩医学院动物实验中心,长春130021 [2]吉林大学体育学院运动人体实验中心,长春130012 |
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| 摘 要： | 目的观察复方红花降压胶囊对高血脂大鼠的治疗效果及其毒性。方法通过对Wistar大鼠饲喂高脂料,导致实验用大鼠产生高血脂模型。对模型动物采用复方红花降压胶囊灌胃治疗。结果复方红花降压胶囊对高血脂大鼠具有降血脂作用,其降脂作用显著。并对机体无毒性作用。结论复方红花降压胶囊对高血脂大鼠有明显降脂作用,为应用于临床治疗高血压提供了理论依据。
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| 关 键 词： | 复方红花降压胶囊 大鼠 高脂料 |
Lipid-lowering Effect and Safety Assessment of the Compound Safflower Buck Capsule in Laboratory Rats |
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| XU Cai-yun,ZHANG Da-wei,BING Guo-qiang,LI Xin-yue,WU Ling-yu.Lipid-lowering Effect and Safety Assessment of the Compound Safflower Buck Capsule in Laboratory Rats[J].Shiyan Dongwu Kexue,2010,27(5):29-32. |
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| Authors: | XU Cai-yun ZHANG Da-wei BING Guo-qiang LI Xin-yue WU Ling-yu |
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| Institution: | 1.Experimental Animal Center,Norman Bethune Medical School,Jilin University,Changchun 130021,China)(2.Sport Science Experiment Center,College of Physical Education,Jilin University,Changchun 130012,China) |
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| Abstract: | Objective To investigate the lipid-lowering effect of the compound safflower buck capsule in hyperlipidemia rats and its toxicity.Methods Hyperlipidemia rat model was established by high-fat feeding,and then administration of compound safflower capsules was performed by oral gavage.Results and Conclusion The compound safflower buck capsule has a significant lipid-lowering effect on hyperlipidemia rats with no toxicity,which provides an experimental basis for clinic application of the compound safflower buck capsule in hyperlipidemia therapy. |
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| Keywords: | Compound safflower buck Rats High-fat feeding |
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