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近交系大,小鼠保种的研究
引用本文:刘恩岐 常档霞. 近交系大,小鼠保种的研究[J]. 实验动物科学, 1997, 14(2): 8-12
作者姓名:刘恩岐 常档霞
作者单位:西安医科大学实验动物中心!西安,710061,西安医科大学实验动物中心!西安,710061
摘    要:本单位从1989年陆续引进了8个国家通用的标准近交系大,小鼠,通过5年多的繁殖和保种实践,我们根据每个品系的特点,逐渐摸索出一套科学的保种方法,设计了保种体系,保证了近交系大,小鼠的遗传质量。

关 键 词:近交系 大鼠 小鼠 保种 繁殖 医用实验动物

Studies on Maintenance of the Inbred Strains of Laboratory Mice and Rats
Liu Enqi, Chang Dangxia. Studies on Maintenance of the Inbred Strains of Laboratory Mice and Rats[J]. Laboratory Animal Science, 1997, 14(2): 8-12
Authors:Liu Enqi   Chang Dangxia
Abstract:Four inbred strains of mice and four inbred strains of rats had been introduced from Beijing since 1989, and maintained in our center. All of these strains, as foundation colonies, were kept according to a modified parallel line system with full brother-sister mating, accompanied with complete pedigree records including breeding record cards, pedigree charts and pedigree books. Up to now, all strains survived to 9~13 generations. We did not find genetic "pollution", with the genetic testing method established by us.other data obtained were normal. The results showed that the method of maintenance is right.
Keywords:Inbred strain Mouse Rat Maintenance
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