Mast cells in the pinna of Balb/c ‘nude’ (nu/nu) and heterozygotes (nu/+) mice |
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| Authors: | K. Wŀodarski |
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| Affiliation: | (1) Department of Immunology and Microbiology, Wayne State University, School of Medicine, 540 E. Canfield Street, 48201 Detroit, Michigan, USA;(2) Present address: Department of Histology, Institute of Biostructure, School of Medicine, PL 02-004 Warsaw, Poland |
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| Abstract: | Summary The relative number of mast cells in the ear lobes' skin (pinna) of nude (athymic) nu/nu and normal (thymic) nu/+ heterozygotes of Balb/c mice was similar. The results obtained contradict some suggestions about the general influence of the thymus on the number of mast cells in the skin and suggest the existence of some local factor(s) in regulation of skin mast cell numbers.This work was supported by grant No. CA16426.The author wishes to thank Dr Kenneth Morrison for supplying the mice and the discussion, Mr Duffy Michowski for taking care of the animals used, Mr Carl Polley for taking the pictures and Dr N. R. Rose for the discussion. |
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