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Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit |
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| Authors: | J Boulter K Evans D Goldman G Martin D Treco S Heinemann J Patrick |
| Abstract: | We have isolated a complementary DNA clone containing sequences homologous to those encoding the alpha-subunit of a mouse muscle nicotinic acetylcholine receptor. Based on the structural similarities between the encoded protein and the muscle acetylcholine receptor alpha-subunit, and the presence of hybridizing RNA species in the brain, we propose that this clone codes for a neural nicotinic acetylcholine receptor alpha-subunit. |
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