对妊娠期巨幼红细胞性贫血造血过程中无丝分裂的一些观察

对直接细胞分裂的研究已有百余年历史,直接分裂究属正常繁殖过程,抑为异常或病理性现象,其说不一,尚难定论。本文在一例重症妊娠期巨幼红细胞性贫血患者的骨髓涂片中发现巨幼红细胞的直接核分裂现象,除了通常的直接核分裂外,尚存在罕见的细胞‘改组’(新核在老核内的形成)及核内无丝分裂。笔者在另一例慢性淋巴细胞白血病患者的骨髓涂片中,亦曾观察到细胞‘改组’现象。因此,笔者认为直接核分裂应属病理性造血过程,即当造血急需时,在通常病理造血过程的同时,亦可出现各型直接分裂以做为造血的补充。这一现象的发现具有造血理论和临床实际意义。

SOME OBSERVATIONS ON AMITOTIC CELL DIVISION DURING HEMOPOIETIC PRQEESS IN A SEVERE CASE OF MEGALOBLASTIC ANEMIA OF EREGNANCY

Some rare types of amitotic cell division in bone marrow smears of a severe ease of megaloblastic anemia of pregnancy were observed. The types of amitotic cell division included direct division, budding, karyorrhexis, reorganization' of cell and endonuclear amitosis. Among which, the 'reorganization' of cell and endonuclear amitosis were very rarely seen in megaloblastic hemopoiesis. As far as the author knows, the present report may be the first within China. The characteristics and significance of these types of division were discussed. It is suggested that when examining the hemopoietic tissue, either smear preparation or section, one ought to observe the phenomena of amitotic cell division. If one can discover the phenomena in the preparations of a normal hemopoietic process, and especially when the amitotic and mitotic divisions appeared in turn, it will be more significant.