Biosynthesis of deuteriated amino acids byCandida lipolytica |
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Authors: | S. Abrahamsson B. Å. Andersson F. Dinger Ng. Dinh-Nguyên L. Hellgren J. Vincent |
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Affiliation: | (1) Department of Structural Chemistry, Faculty of Medicine, University of Göteborg, Göteborg, (Sweden);(2) Department of Dermatology, Sahlgren's Hospital, Göteborg, (Sweden);(3) Medicinaregatan 9, University of Göteborg, Structural Chemistry, S-400 33 Göteborg 33, Sweden |
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Abstract: | Summary Biosynthesis of a whole series of deuteriated amino acids has been carried out, by cultivation of the yeastCandida lipolytica in an artificial medium composed of a deuterio-alkane, heavy water, water and some mineral salts.Acknowledgments. This work has been carried out with the aid of grants from The Swedish Medical Research Council. Thanks are due to Mr Nils Engström for his skilful technical assistance during the yeast growth, and to Mrs Monica Olsson for the Moore-Stein analysis. |
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