早期干预对新生儿缺氧缺血性脑病预后影响的综合评估

目的：探讨早期干预对减少中重度缺氧缺血性脑病（HIE）患儿脑瘫、精神发育迟滞等后遗症的作用。方法：将118例中、重度HIE患儿按入院顺序分单号为干预组（A组）66例，双号为对照组（B组）52例。对A组从1个月起进行早期干预至24个月。结果：24个月时A组患儿智能发育指数（MDI），运动发育指数（PDI），社会适应能力明显高于B组（P〈0．05），而脑瘫的发生率明显低于B组。结论：对HIE患儿进行早期干预能显著减少脑瘫、精神发育迟滞等后遗症的发生，改善其预后。

Assessment of Prognosis of Hypoxic-Ischemic Encephalopathy (HIE) after Early Intervention

Objective: To explore the prognosis of hypoxic-ischemic encephalopathy(HIE)after early interventio,and reduction of cerebral palsy and mental retardation.Methods: 118 cases of HIE were divided into experimental group(66 cases)and control group(52 cases)at random.Early intervention was given to the experimental group from the first month to the 24th month.Results: Up to the 24th month,MDI and PDI and social competence of the experimental group were higher than that of the control group(P<0.05).The incidence of cerebral palsy was lower.Conclusion: Early intervention could markedly reduce the incidence of cerebral palsy and mental retardation,and thus improve prognosis.