In vitro characterization of adrenergic receptors mediating extrusion of preformed sebum from preputial gland of rat

Summary Extrusion of preformed sebum from the preputial glands of rat after phenylephrine and adrenaline treatment, and its inhibition by -receptor blocking agents under in vitro conditions, shows that secretory response of the glands is influenced by -adrenergic receptors, and isoproterenol — a -agonist — is not effective in elicitation of exudation of secretion from the preputial gland.Acknowledgements. We are thankful to Prof. R.V. Shah, for providing the facilities to conduct this work. D.M. V. is grateful to the Indian Council of Medical Research for the award of a Senior Research Fellowship during the tenure of which this work was conducted.