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妊高征血浆内皮素,降钙素基因相关肽变化
引用本文:李继红,罗晓阳.妊高征血浆内皮素,降钙素基因相关肽变化[J].甘肃科学学报,1998,10(3):69-71.
作者姓名:李继红  罗晓阳
作者单位:[1]珠海市妇幼保健医院 [2]中国人民解放军第473医院
摘    要:分正常妊娠组和妊高征组,用RIA法测定患者血浆ET-1、CGRP含量,同时常规测定血浆BUN、Cr,结果表明妊高征组患者血浆ET-1、BUN、Cr水平均明显高于正常妊娠组,同时CGRP明显低于正常妊娠组;且随着病情加重ET-1水平逐渐升高。血浆ET-1、CGRP含量间存在显著负相关性。说明ET-1水平增高、CGRP水平下降是引起妊高征病理生理变化的重要因素。

关 键 词:高血压  血浆  内皮素  妊高征  CGRP  妊娠并发病

LEVELS OF ENDOTHELIN 1 AND CALCITONIN GENE RELATED PEPTIDE IN THE PLASMA IN PATIENTS WITH PREGNANCE INDUCED HYPERTENSION
Li Jihong\ Liu Jiang\ Zhou Dang.LEVELS OF ENDOTHELIN 1 AND CALCITONIN GENE RELATED PEPTIDE IN THE PLASMA IN PATIENTS WITH PREGNANCE INDUCED HYPERTENSION[J].Journal of Gansu Sciences,1998,10(3):69-71.
Authors:Li Jihong\ Liu Jiang\ Zhou Dang
Abstract:In order to observe the levels of ET 1 and CGRP in the plasma in patients with pregnancy induced hypertension.The levels of endothelin 1 (ET 1) and calciton in gene related peptide in the plasma in Patients with Pregnangcy indued hypertension were determined by RIA.The result showed that the levels of ET 1 in the plasma in patients with pregnancy induced hypertension increased significantly as compared with those in the control group;but the levels of CGRP in the plasma were correlated negatively and markedly with those of ET 1.It is suggested that ET 1 and CGRP may play some important roles in pathophsiology of pregnancy induced hypertension.
Keywords:Pregnancy  Induced Hypertension  endothelin 1  calcitonin gene related peptide
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