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心肌宁冲剂对感染柯萨奇B_3病毒小鼠的保护作用
引用本文:崔新颖,吕俊华,张成义,王北辰,李国立,齐秉均.心肌宁冲剂对感染柯萨奇B_3病毒小鼠的保护作用[J].北华大学学报(自然科学版),1995(3).
作者姓名:崔新颖  吕俊华  张成义  王北辰  李国立  齐秉均
作者单位:吉林医学院药理教研室 (崔新颖,吕俊华,张成义,王北辰),吉林医学院病理教研室 (李国立),吉林医学院病理教研室(齐秉均)
摘    要:本文采用4W龄Babl/c小鼠,腹腔内感染,CB_3病毒并给于心肌宁治疗。结果表明:心肌宁冲剂对感染CB_3病毒的小鼠可明显提高其体内中和抗体水平,减少细胞坏死率,明显减弱病毒毒力,病理学检查显示:心肌变性坏死显著减轻,炎性渗出减少,纤维组织增生较早且明显。

关 键 词:心肌宁  柯萨奇B_3病毒  心肌炎

The Protective Effects of Xin Jining chongji on Mice Infected with CB_3 Virus.
Cui Cinying et al.The Protective Effects of Xin Jining chongji on Mice Infected with CB_3 Virus.[J].Journal of Beihua University(Natural Science),1995(3).
Authors:Cui Cinying
Institution:Department of pharmacology
Abstract:Balb/c mice, 4 weeks after birth, were infected with CB3 virus intra- peritoneally and treated with Xin Jining.The results showed that Xin Jining increased the level of neutralizing antibodies significantly, reduced the ratio of cellular necrosis, and attenuated the virulence of virus significantly. Patholohgical exam. showed that the degeneration and necrosis of myocardium were relieved significantly with reduction of inflammatory exudates and earlier and more prominent hy-perplasia of fibrous tissues.
Keywords:CB3 virus Myocarditis Xin Jining    
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