| 固-液相转移催化合成1-氰基环丁烷-1-羧酸乙酯 |
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| 引用本文： | 宋瑞峰,王玉红.固-液相转移催化合成1-氰基环丁烷-1-羧酸乙酯[J].苏州科技学院学报(自然科学版),2000(3). |
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| 作者姓名： | 宋瑞峰 王玉红 |
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| 作者单位： | 苏州铁道师范学院化学系!苏州215009 |
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| 摘 要： | 以PEG6 0 0为相转移催化剂 ,无水碳酸钾为碱 ,1 ,2 -二氯乙烷为溶剂 ;氰基乙酸乙酯和 1 ,3-二溴丙烷为反应原料 ,经缩合反应较高产率的合成 1 -氰基环丁烷- 1 -羧酸乙酯 ,收率达 6 4 % ,此方法反应条件温和 ,原料便宜易得 ,操作简便安全。
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| 关 键 词： | 氰基乙酸乙酯 相转移催化 合成 1-氰基环丁烷-1-羧酸乙酯 1 3-二溴丙烷 |
Solid-liquid Phase-tranfercatalytic Synthesis of 1-cyanocyclobutane-1-ethylacetate |
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| SONG Rui feng,WANG Yu hong.Solid-liquid Phase-tranfercatalytic Synthesis of 1-cyanocyclobutane-1-ethylacetate[J].Journal of University of Science and Technology of Suzhou,2000(3). |
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| Authors: | SONG Rui feng WANG Yu hong |
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| Abstract: | cyanocyclobutane-1-ethylacetate was synthesized in good yield(64%)from the reaction of ethylcyanoacetate with 1,3-dibromopropane using PEG600 as a phase-transfer catalyst,anhydrous potassium as base and 1,2-dichlroethane as solvent. Advantages of the present method are the excellent yields,mild reaction conditions,and operational simplicity. |
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| Keywords: | ethylcyanoacetate phase-transfer catalysis synthesis 1-cyanocyclobutane-1-ethylacetate 1 3-dibromopropane |
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