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Loss of cytosolic serine hydroxymethyltransferase in a formate mutant ofNeurospora crassa
Authors:E A Cossins  Sophie H Y Pang
Institution:(1) Department of Botany, University of Alberta, T6G 2E9 Edmonton, Alberta, Canada
Abstract:Summary In the wild type ofNeurospora crassa serine hydroxymethyltransferase occurs in the cytosol and mitochondria. The formate mutant (FGSC 9) lacks the cytosolic activity but has increased levels of isocitrate lyase and glyoxylate aminotransferase. Glycine is derived from glyoxylate in the mutant.
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