Änderung des Glukosetransports frischer menschlicher Erythrozyten bei längerer Inkubation

Summary Incubation of fresh defibrinated blood at 37°C increases the volume of red cells and decreases their permeation rate for glucose. The kinetics of sugar transport show direct proportionality between rate and the osmotic content of red cells. The measured volume changes and the changes of osmotic content calculated from the glucose permeation curves are in good agreement. Adenosine reconstitutes the increased volume and the decreased permeation rate in red cells. Therefore the decrease in permeation rate is explained by the increase in volume.