Molecular recognition: models for drug design. |
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Authors: | R J Breckenridge |
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Affiliation: | Drug Design Group, Sandoz Pharma Ltd., Basel, Switzerland. |
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Abstract: | The review takes examples, mostly from the recent literature, to illustrate how an understanding of physico-chemical properties and an appreciation of the molecular shape and electronic properties can lead to a better insight into molecular recognition processes. The techniques used to generate 3-dimensional structures of molecules and the influence this information has had on the drug design cycle, are briefly discussed. |
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