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Molecular recognition: models for drug design.
Authors:R J Breckenridge
Affiliation:Drug Design Group, Sandoz Pharma Ltd., Basel, Switzerland.
Abstract:The review takes examples, mostly from the recent literature, to illustrate how an understanding of physico-chemical properties and an appreciation of the molecular shape and electronic properties can lead to a better insight into molecular recognition processes. The techniques used to generate 3-dimensional structures of molecules and the influence this information has had on the drug design cycle, are briefly discussed.
Keywords:
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