Stimulating effect of thromboxane B2 on isolated rat atria |
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| Authors: | L Sterin-Borda L Canga A L Gimeno |
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| Institution: | (1) Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina (CONICET), V. de Obligado 2490, 1428 Buenos Aires, Argentina |
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| Abstract: | Summary Thromboxane B2 enhanced the beating frequency and the contractile tension of isolated rat atria. Both effects were inhibited by propranolol, by pretreatment with 6-hydroxydopamine, or after inhibition of prostaglandins synthesis with indomethacin and acetylsalicylic acid.This work has been supported by grant 6638 from CONICET (Argentina). |
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