| IL-17在胃癌组织中的表达及其与微血管生成的相关性分析 |
| |
| 引用本文： | 苏涛. IL-17在胃癌组织中的表达及其与微血管生成的相关性分析[J]. 科学技术与工程, 2011, 11(13): 2893-2896 |
| |
| 作者姓名： | 苏涛 |
| |
| 作者单位： | 1. 第四军医大学西京消化病医院,西安,710032
2. 中国人民解放军总医院,北京,100853 |
| |
| 摘 要： | 为探讨胃癌患者肿瘤组织中IL-17的表达及其与微血管生成的关系,采用免疫组织化学染色检测IL-17在30例胃癌患者石蜡包埋肿瘤组织中的表达,分析IL-17阳性细胞的形态学特征;对上述胃癌组织进行CD34免疫组织化学染色,计数微血管生成;统计学分析胃癌组织中IL-17表达与微血管生成的关系。结果在人类胃癌组织中IL-17阳性细胞多呈淋巴细胞样特征,且其表达水平较高组微血管生成增多。说明胃癌组织中IL-17表达水平与微血管生成正相关。
|
| 关 键 词： | IL-17 胃癌 微血管生成 |
| 收稿时间： | 2011-02-23 |
| 修稿时间： | 2011-02-23 |
The expression of IL-17 correlates with angiogenesis in gastric cancer tissues |
| |
| sutao. The expression of IL-17 correlates with angiogenesis in gastric cancer tissues[J]. Science Technology and Engineering, 2011, 11(13): 2893-2896 |
| |
| Authors: | sutao |
| |
| Affiliation: | 2(Xijing Hospital of Digestive Disease,Fourth Military Medical University1,Xi’an 710032,P.R.China;The General Hospital of the People’s Liberation Army2,Beijing 100853,P.R.China) |
| |
| Abstract: | Abstract: To investigate the potential relationship between IL-17 expression and angiogenesis in human gastric cancer, immunohistochemistry was performed to examine the expression of IL-17 and CD34 in 30 paraffin-embedded gastric cancer tissues. The results showed that most of the IL-17-positive cells exhibited the lymphocyte-like feature and the number correlated with the microvessel density(r=o.642,P<0.001). In conclusion, these is a positive correlation between IL-17 expression and the microvessel density and IL-17 may contribute to angiogenesis in gastric cancer. |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《科学技术与工程》浏览原始摘要信息 |
|
点击此处可从《科学技术与工程》下载全文 |
|
