Gametes contain angiotensin converting enzyme (kininase II) |
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| Authors: | J R Brentjens S Matsuo G A Andres P R B Caldwell L Zamboni |
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| Institution: | (1) Department of Pathology, Microbiology and Medicine, State University of New York at Buffalo, 204 Farber Hall, 14214 Buffalo, New York, USA;(2) Present address: Department of Medicine, Columbia University, 10032 New York, N.Y., USA;(3) Present address: Department of Pathology, Harbor-UCLA Medical Center, 90509 Torrance, CA, USA |
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| Abstract: | Summary The localization of angiotensin converting enzyme (ACE) in the gonads of the normal rabbit was studied by immunofluorescence and immunoelectron microscopy. The enzyme is present in the cytoplasm of testicular spermatids and of epididymal and ejaculated spermatozoa, and on the surface of follicular and tubal cocytes. These findings support the hypothesis that ACE has a role in gamete maturation and in fertilization.Acknowledgments. This study was supported by NIH grant AM36807 and by grants from the American Heart Association, the Joe and Emily Lowe Foundation, and the Dana Foundation. We thank L. Fernandez, B. Luders, I. Pawlowski, and K. Schwegler for technical assistance. |
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| Keywords: | Angiotensin converting enzyme rabbit gametes rabbit Leydig cells |
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