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剪切模量和粘度对HIFU微泡增效治疗声场影响的数值仿真
引用本文:王鹏,喻波涛,常诗卉,吴世敬,菅喜岐.剪切模量和粘度对HIFU微泡增效治疗声场影响的数值仿真[J].北京理工大学学报,2017,37(S1):88-92.
作者姓名:王鹏  喻波涛  常诗卉  吴世敬  菅喜岐
作者单位:天津医科大学 生物医学工程与技术学院, 天津 300070,天津医科大学 生物医学工程与技术学院, 天津 300070,天津医科大学 生物医学工程与技术学院, 天津 300070,天津医科大学 生物医学工程与技术学院, 天津 300070,天津医科大学 生物医学工程与技术学院, 天津 300070
基金项目:国家自然科学基金项目资助(81272495)
摘    要:研究剪切模量和粘度对HIFU微泡治疗声压场的影响.利用气液混合声波传播方程、Yang-Church气泡运动方程、时域有限差分(FDTD)法和龙格-库塔(RK)法建立含微泡的单阵元换能器数值仿真模型,分别改变模型中仿组织体模的剪切模量和粘度,研究其对形成声压场的影响.仿真结果表明,随着剪切模量的增大,焦域中心声压逐渐降低且焦域位置向靠近换能器方向移动;随着粘度的增大,焦域中心声压逐渐降低,焦域位置几乎不变.

关 键 词:高强度聚焦超声  剪切模量  粘度  微泡  数值仿真
收稿时间:2016/11/19 0:00:00

Numerical Simulation of the Influence of Shear Modulus and Viscosity to the Ultrasound Field of Microbubble Enhanced High Intensity Focused Ultrasound
WANG Peng,YU Bo-tao,CHANG Shi-hui,WU Shi-jing and JIAN Xi-qi.Numerical Simulation of the Influence of Shear Modulus and Viscosity to the Ultrasound Field of Microbubble Enhanced High Intensity Focused Ultrasound[J].Journal of Beijing Institute of Technology(Natural Science Edition),2017,37(S1):88-92.
Authors:WANG Peng  YU Bo-tao  CHANG Shi-hui  WU Shi-jing and JIAN Xi-qi
Institution:Department of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China,Department of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China,Department of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China,Department of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China and Department of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China
Abstract:The influence of shear modulus and viscosity to the ultrasound field of microbubble enhanced high intensity focused ultrasound was discussed.The numerical simulation model was established based on the gas-liquid mixing acoustic propagation equation, Yang-Church bubble motion equation, the finite difference time domain (FDTD) method and Runge-Kutta (RK) method. The HIFU pressure field with different shear modulus and viscosity of tissue mimicking phantom was evaluated.The results showed that, as the shear modulus increasing, the pressure at focus decreases and the focus move closer to the transducer side; as the viscosity increasing, the pressure at focus increases and the focus position without clear shift.
Keywords:high-intensity focused ultrasound  shear modulus  viscosty  microbubbles  numerical simulation
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