| 真菌来源含[2.2.2]-环二氮辛烷环系统的异戊烯基吲哚生物碱 |
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| 引用本文： | 黄艳冰,何其欢,梁永源,甘永霞,潘丽霞,杨登峰.真菌来源含[2.2.2]-环二氮辛烷环系统的异戊烯基吲哚生物碱[J].广西科学,2020,27(1):40-48. |
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| 作者姓名： | 黄艳冰 何其欢 梁永源 甘永霞 潘丽霞 杨登峰 |
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| 作者单位： | 广西科学院北部湾海洋研究中心, 广西海洋天然产物与组合生物合成化学重点实验室, 广西南宁 530007,广西科学院北部湾海洋研究中心, 广西海洋天然产物与组合生物合成化学重点实验室, 广西南宁 530007,广西科学院北部湾海洋研究中心, 广西海洋天然产物与组合生物合成化学重点实验室, 广西南宁 530007,广西科学院北部湾海洋研究中心, 广西海洋天然产物与组合生物合成化学重点实验室, 广西南宁 530007,广西科学院国家非粮生物质能源工程技术研究中心, 非粮生物质酶解国家重点实验室, 广西南宁 530007,广西科学院北部湾海洋研究中心, 广西海洋天然产物与组合生物合成化学重点实验室, 广西南宁 530007 |
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| 基金项目： | 国家自然科学基金项目（31660251，31860245，31960203）和广西自然科学基金项目（2017GXNSFAA198010，2018GXNSFAA138024，2018GXNSFAA281019）资助。 |
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| 摘 要： | 近年来,真菌因其种类繁多、分布广泛,且能够产生大量结构新颖、活性显著的代谢产物而受到广泛关注。本文综述了从真菌中分离得到的含2.2.2]-环二氮辛烷环系统的异戊烯基吲哚生物碱的结构及生物活性,其中包括malbrancheamides类、brevianamides类、chrysogenamides类、marcfortines类、paraherquamides类、asperparalines类、stephacidins类和notoamides类。真菌来源含2.2.2]-环二氮辛烷环结构的异戊烯基吲哚生物碱不仅结构奇特,并且表现出多种重要的生物活性,具有潜在的研究和应用价值。
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| 关 键 词： | 真菌 二酮哌嗪 异戊烯基吲哚生物碱 [2.2.2]-环二氮辛烷环 生物活性 |
Fungi Origins of the Bicyclo [2.2.2] Diazaoctane Ring System of Prenylated Indole Alkaloids |
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| HUANG Yanbing,HE Qihuan,LIANG Yongyuan,GAN Yongxi,PAN Lixia and YANG Dengfeng.Fungi Origins of the Bicyclo [2.2.2] Diazaoctane Ring System of Prenylated Indole Alkaloids[J].Guangxi Sciences,2020,27(1):40-48. |
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| Authors: | HUANG Yanbing HE Qihuan LIANG Yongyuan GAN Yongxi PAN Lixia and YANG Dengfeng |
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| Institution: | Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry, Beibu Gulf Marine Research Center, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China,Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry, Beibu Gulf Marine Research Center, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China,Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry, Beibu Gulf Marine Research Center, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China,Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry, Beibu Gulf Marine Research Center, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China,National Engineering Research Center for Non-Food Biorefinery, State Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China and Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry, Beibu Gulf Marine Research Center, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China |
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| Abstract: | In recent years,fungi have attracted extensive attention because of their species diversity and wide distribution,which can produce a large number of metabolites with novel structure and significant activity.In this paper,the structure and bioactivity of the bicyclo2.2.2] diazaoctane ring system of prenylated indole alkaloids from fungi were reviewed,including malbrancheamides,brevianamides,chrysogenamides,marcfortines,paraherquamides,asperparalines,stephacidins,notoamides.This bicyclo2.2.2] diazaoctane ring system of prenylated indole alkaloids from fungi not only have peculiar structures,but also exhibit a variety of important biological activities,which have potential research and application value. |
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| Keywords: | fungi diketopiperazines prenylated indole alkaloids bicyclo [2 2 2] diazaoctane ring biological activities |
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