| 新疆骆驼刺植物抗过敏作用的研究 |
| |
| 引用本文： | 张雪梅,张黎明.新疆骆驼刺植物抗过敏作用的研究[J].科技信息,2010(19):33-34. |
| |
| 作者姓名： | 张雪梅 张黎明 |
| |
| 作者单位： | [1]伊犁师范学院,新疆伊宁835100 [2]伊犁州质量技术监督局,新疆伊宁835100 |
| |
| 摘 要： | 目的：研究新疆骆驼刺提取物的抗过敏作用及其机制。方法：抗过敏动物模型实验法及大鼠嗜碱性白血病细胞株RBL-2H3活化脱颗粒,ELISA酶联免疫法测试组胺过敏活性介质浓度。结果：骆驼刺提取物对致敏豚鼠离体回肠收缩有显著性拮抗作用,对RBL-2H3细胞脱颗粒释放组胺有显著性抑制作用,作用效果与色甘酸钠组相近。结论：骆驼刺的抗过敏作用机制可能是通过抑制MC细胞内活化信号的传导,从而抑制MC释放炎症介质,达到抗过敏作用效果。
|
| 关 键 词： | 骆驼刺提取物 抗过敏 RBL-2H3细胞 组胺 |
Effect of theExtraction of Alhagi Pseudalhagi on Anti-allergic Activity and Its Mechanism |
| |
| Abstract: | Objective： To determine the direct effect of the extraction of Alhagi pesudalhagi on the anti-allergic activity.Method：We build the allergic animal model and uesed the compound48/80 to induced RBL-2H3 cells degranulation to measure their vitro anti-allergic effrct.The histamine from the supernatants were measured by ELISA.Resuhs：The extraction obviously suppressed the histamine,its inhibiting effect was comparable to sodium eromoglicate control group.Conclusion： Alhagi pesudalhagi suppressed degranulation of RBL-2H3 mast ceils may be one of the mechanisms of type-I allergic reaction in the treatment of diseases. |
| |
| Keywords: | Extraction of Alhagi pesudalhagi Anti-allergic RBL-2H3 cells Histamine |
| 本文献已被 维普 等数据库收录！ |
|
