| 金铃子散的半仿生提取及抗癌活性研究 |
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| 引用本文： | 戴一,艾甜碧. 金铃子散的半仿生提取及抗癌活性研究[J]. 井冈山大学学报(自然科学版), 2018, 0(3): 98-101 |
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| 作者姓名： | 戴一 艾甜碧 |
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| 作者单位： | 安徽新华学院药学院 |
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| 基金项目： | 安徽省教育厅自然科学研究重点项目（KJ2016A301）;国家级大学生创新创业训练计划创新（201412216005） |
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| 摘 要： | 目的研究金铃子散的半仿生提取及抗癌活性。方法将金铃子散进行半仿生提取,提取物通过MTT法研究其抗癌活性。结果金铃子散用含20%乙醇的半仿生液提取效果较佳,且抗癌活性较好,尤其对人肝癌Hep G2细胞具有抗癌活性。结论金铃子散半仿生提取物均表现出一定的抗癌活性,为其临床抗癌应用提供科学依据。
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| 关 键 词： | 金铃子散 半仿生提取 抗癌活性 |
| 收稿时间： | 2018-01-02 |
| 修稿时间： | 2018-03-02 |
SEMI-BIONIC EXTRACTION AND ANTICANCER ACTIVITY OF JINLINGZI SAN |
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| DAI Yi and AI Tian-bi. SEMI-BIONIC EXTRACTION AND ANTICANCER ACTIVITY OF JINLINGZI SAN[J]. Journal of Jinggangshan University(Natural Sciences Edition), 2018, 0(3): 98-101 |
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| Authors: | DAI Yi and AI Tian-bi |
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| Affiliation: | School of Pharmaceutical Sciences, Anhui Xinhua College, Hefei, Anhui 230088, China and School of Pharmaceutical Sciences, Anhui Xinhua College, Hefei, Anhui 230088, China |
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| Abstract: | Objective: To explore semi-bionic extraction and anticancer activity of Jilingzi San. Methods: Jinlingzi San was extracted by semi-bionic extraction and the extracts were assayed by MTT to study the anticancer activity. Results: Jinlingzi San could be extracted well by solution of semi-bionic extraction containing 20% ethanol to get the best active fraction against cancer cell, especially HepG2 cell. Conclusion: Semi-bionic extraction of Jilingzi San had anticancer activity, which provided the reference for clinical application. |
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| Keywords: | Jinlingzi San semi-bionic extraction anticancer activity |
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