有机立体化学构型判断及互换

通过举例介绍了有机立体化学中透视式和Fischer投影式中手性碳原子的R/S构型最基本判断法则。在立体化学的重点和难点——Newman投影式、透视式与Fischer投影式之间的相互转换等方面,针对空间想象能力较薄弱的初学者,在遵循该法则的基础上,结合教学实践及教学实例,引导学生发现规律,探讨总结出一套有效的经验方法。使学生不再依赖分子模型的辅助,准确地实现分子各种立体结构式之间的相互转换,有助于同学们理解烯烃的亲电加成反应、卤代烃和醇的消除反应的立体化学并可以解决相关问题。

Judgement Configuration and Mutual Conversion Techniques in Organic Stereochemistry

By exemplification, the author discussed the fundamental judgment rules of the R、S configuration of chiral carbon atom in organic stereochemistry's perspective and Fischer's Projection.Using this rule, it can help students learn and summary the effective method on the mutual transformation of Newman's Projection, perspective and Fisher's Projection in stereochemistry.As a result, students can transfer the dimensional structure of molecules and will no longer rely on the auxiliary of molecular models . This is beneficial to students to understand and solve the relevant questions in stereochemistry , such as the electrophilic addition reaction of olefins, elimination reaction of halogenated hydrocarbon and alcohol.