| 4,6-二芳基-4,5-二氢-3-羟基-1(1H)-吲唑衍生物的微波促进合成及抗细菌活性评价 |
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| 引用本文： | 李小六,王彦坡,陈华,赵莲,曹克强. 4,6-二芳基-4,5-二氢-3-羟基-1(1H)-吲唑衍生物的微波促进合成及抗细菌活性评价[J]. 河北大学学报(自然科学版), 2008, 28(1): 39-45. DOI: 10.3969/j.issn.1000-1565.2008.01.012 |
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| 作者姓名： | 李小六 王彦坡 陈华 赵莲 曹克强 |
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| 作者单位： | 河北大学,化学与环境科学学院,河北,保定,071002;河北农业大学,植物保护学院,河北,保定,071001 |
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| 基金项目： | 河北省自然科学基金 , 河北省教育厅自然科学基金 |
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| 摘 要： | 利用微波促进有机合成的方法,以查尔酮为起始物,合成了系列的4,6-二芳基-4,5-二氢-3-羟基-1(1H)-吲唑衍生物,并对其结构及互变异构现象进行了研究,初步测定了化合物的抗细菌活性.
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| 关 键 词： | 吲唑 4 5-二氢-1(1H)-吲唑 微波 |
| 文章编号： | 1000-1565(2008)01-0039-07 |
| 修稿时间： | 2007-09-29 |
Microwave Assisted Synthesis and Antibacterial Activity of 4,6-Diaryl-4,5-dihydro-3-hydroxy-1H-indazole Derivatives |
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| LI Xiao-liu,WANG Yan-po,CHEN Hua,ZHAO Lian,CAO Ke-qiang. Microwave Assisted Synthesis and Antibacterial Activity of 4,6-Diaryl-4,5-dihydro-3-hydroxy-1H-indazole Derivatives[J]. Journal of Hebei University (Natural Science Edition), 2008, 28(1): 39-45. DOI: 10.3969/j.issn.1000-1565.2008.01.012 |
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| Authors: | LI Xiao-liu WANG Yan-po CHEN Hua ZHAO Lian CAO Ke-qiang |
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| Abstract: | A series of 4,6-diaryl-4,5-dihydro-3-hydroxy-1H-indazole derivatives have been prepared from chalcones in good yield with assisted microwave irradiation,providing a facile method for the preparation of 4,5-dihydro-1H-indazole derivatives.The structures and tautomerism of the derivatives were investigated,and the antibacterial activity of the compounds was also evaluated. |
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| Keywords: | indazole 4,5-dihydro-1H-indazole microwave |
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