| 不同产地两面针果壳挥发油化学成分及其抗肿瘤活性 |
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| 引用本文： | 柴玲,刘布鸣,林霄,赖茂祥,蒋珍藕.不同产地两面针果壳挥发油化学成分及其抗肿瘤活性[J].广西科学,2018,25(2):223-228. |
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| 作者姓名： | 柴玲 刘布鸣 林霄 赖茂祥 蒋珍藕 |
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| 作者单位： | 广西中医药研究院广西中药质量标准研究重点实验室 |
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| 基金项目： | 广西科学研究与技术开发计划项目(桂科重1598005-12),玉林市科学研究与技术开发计划项目(玉市科攻1535015)资助 |
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| 摘 要： | 【目的】研究不同产地两面针果壳挥发油的化学成分及其抗肿瘤活性,并比较不同产地两面针果壳挥发油的主要化学成分及含量差异,为两面针植物的综合开发利用提供科学依据。【方法】采用水蒸气蒸馏法提取两面针果壳挥发油,应用GC毛细管柱进行分离,质谱检测,面积归一化法测定其相对含量。采用MTT法检测挥发油对宫颈癌细胞(Hela)、乳腺腺癌细胞(MCF-7)、肺腺癌细胞(A549)、胃癌细胞(MGC-803)、结肠癌细胞(COLO-205)的增殖影响。【结果】不同产地两面针果壳挥发油主要成分基本相同,以烯醇类成分为主,其中芳樟醇含量最高,其次为β-蒎烯、β-水芹烯。MTT法提示两面针果壳挥发油可抑制Hela、MCF-7、A549、MGC-803和COLO-205细胞的生长。【结论】不同产地两面针果壳挥发油主要成分基本相同,但含量有差异。两面针果壳挥发油对Hela、MCF-7、A549、MGC-803和COLO-205细胞增殖有抑制作用。
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| 关 键 词： | 两面针 果壳 挥发油 化学成分 抗肿瘤活性 |
| 收稿时间： | 2018/1/6 0:00:00 |
| 修稿时间： | 2018/3/5 0:00:00 |
Chemical Constituents and Antitumor Activities Research of Essential Oil of the Fruit Shell of Zanthoxylum nitidum (Roxb.)DC.From Different Areas |
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| CHAI Ling,LIU Buming,LIN Xiao,LAI Maoxiang and JIANG Zhen''ou.Chemical Constituents and Antitumor Activities Research of Essential Oil of the Fruit Shell of Zanthoxylum nitidum (Roxb.)DC.From Different Areas[J].Guangxi Sciences,2018,25(2):223-228. |
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| Authors: | CHAI Ling LIU Buming LIN Xiao LAI Maoxiang and JIANG Zhen'ou |
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| Institution: | Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Science, Nanning, Guangxi, 530022, China,Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Science, Nanning, Guangxi, 530022, China,Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Science, Nanning, Guangxi, 530022, China,Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Science, Nanning, Guangxi, 530022, China and Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Traditional Medical and Pharmaceutical Science, Nanning, Guangxi, 530022, China |
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| Abstract: | |
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| Keywords: | Zanthoxylum nitidum (Roxb )DC fruit shell volatile oil constituents antitumor activities |
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