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Efficient CAN catalyzed synthesis of 1H-indazolo[1,2-b] phthalazine-1,6,11-triones: An eco-friendly protocol
Authors:Kidwai Mazaahir  Chauhan Ritika  Jahan Anwar
Affiliation:1. Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007, India
Abstract:A convenient,economical and green approach to the synthesis of 1H-indazolo[1,2-b]phthalazine-1,6,11-trione derivatives has been achieved via a one-pot protocol using phthalhydrazide,a cyclic-β-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol.The simple work up,mild conditions,excellent yields,inexpensive and non-toxic catalyst and simple solvent recyclability render this protocol both attractive and economically viable.
Keywords:ceric ammonium nitrate  polyethylene glycol  1H-indazolo[1  2-b]phthalazine-1  6  11-triones  recyclability  green chemistry
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