| Immunolocalization of aromatase, estrogen and estrogen receptor α and β in the epithelium of digestive tract and enteric neurons of amphioxus (Branchiostoma belcheri ) |
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| 作者姓名： | FANG Yongqiang WENG Youzhu YE Rongzhong LIU Lili |
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| 作者单位： | The Third Institute of Oceanography of the State Oceanic Administration,Xiamen 361005,China,The Third Institute of Oceanography of the State Oceanic Administration,Xiamen 361005,China,The Third Institute of Oceanography of the State Oceanic Administration,Xiamen 361005,China,The Third Institute of Oceanography of the State Oceanic Administration,Xiamen 361005,China |
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| 基金项目： | Supported by National Natural Science Foundation of China (Grant No. 30070106) |
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| 摘 要： | Immunohistochemical localization of aromatase, estrogen and estrogen receptor in the digestive tract and enteric neurons of amphioxus is investigated. It was found that immunoreactive proteins of aromatase, estrogen and ER-α and β are expressed in hepatic diverticulum, epithelial cells of anterior and posterior region of midgut, as well as in enteric neurons, while hindgut showed immunonegative. The results suggest that digestive tract of amphioxus may be able to synthesize estrogen and possess endocrine function, like rat gastric epithelium and enteric neurons in mammals. The present study provides authentic morphological evidence for explaining the action mechanism of estrogen in regulating the digestive function of gut and the functional evolution of estrogen, which has important theoretical significance in amphioxus.
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| 关 键 词： | amphioxus digestive tract estrogen estrogen receptor α and β aromatase |
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