| 磁性纳米粒子成像高灵敏度正交接收系统 |
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| 引用本文： | 史玥婷,任仕伟,王晓华,薛丞博.磁性纳米粒子成像高灵敏度正交接收系统[J].北京理工大学学报,2022,42(3):312-317. |
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| 作者姓名： | 史玥婷 任仕伟 王晓华 薛丞博 |
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| 作者单位： | 1.北京理工大学 集成电路与电子学院， 北京 100081 |
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| 基金项目： | 重庆市自然科学基金资助项目（cstc2021jcyj-msxmX1090）； |
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| 摘 要： | 本文通过有限元分析设计高灵敏度磁性纳米粒子成像正交接收系统，提升MPI信号检测灵敏度和磁场匀质性，用于预临床小动物级MPI成像。设计的正交接收线圈组新增加x向接收线圈，并且在z向优化了成像视野面积与接收灵敏度，在预临床小动物级MPI成像平台中经过仿真验证、制备、调试、校验，完成了模型成像和小动物成像实验，结果表明本文方法有效提升了图像质量和图像对比度.
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| 关 键 词： | 磁性纳米粒子成像 正交线圈组 接收灵敏度 磁场匀质性 |
| 收稿时间： | 2021-11-15 |
High Sensitivity Orthogonal Receiving System for Preclinical Magnetic Particle Imaging |
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| SHI Yueting,REN Shiwei,WANG Xiaohua,XUE Chengbo.High Sensitivity Orthogonal Receiving System for Preclinical Magnetic Particle Imaging[J].Journal of Beijing Institute of Technology(Natural Science Edition),2022,42(3):312-317. |
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| Authors: | SHI Yueting REN Shiwei WANG Xiaohua XUE Chengbo |
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| Institution: | 1.School of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, China2.Yangtze Delta Region Academy ,Beijing Institute of Technology, Jiaxing, Zhejiang 314019, China3.Chongqing Center for Microelectronics and Microsystems, Beijing Institute of Technology,Chongqing 401332, China |
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| Abstract: | In this paper, a high-sensitivity orthogonal receiving system was designed based on finite-unit analysis to improve MPI signal detection sensitivity and magnetic field homogeneity for preclinical MPI of small animal imaging. The orthogonal receiving coil set was designed to add a new x-direction receiving coil, to improve the reception sensitivity and optimize imaging field of view area in z-direction. Simulation experiments, construction and calibration were carried out in the preclinical MPI platform with the high sensitivity orthogonal receiving systems to perform phantom imaging and small animal imaging experiments. Results show that the new orthogonal system can improve the image quality and contrast-noise rate effectively. |
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