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不同剂型生脉散对氧自由基清除作用的比较
引用本文:余庆皋,王晓春,钟飞. 不同剂型生脉散对氧自由基清除作用的比较[J]. 吉首大学学报(自然科学版), 2007, 28(3): 123-125
作者姓名:余庆皋  王晓春  钟飞
作者单位:湘潭职业技术学院医学院,湖南,湘潭,411100;中南大学湘雅医学院,湖南,长沙,410078;吉首大学医学院,湖南,吉首,416000
摘    要:研究了生脉注射液、生脉饮、生脉胶囊这3种直接用于临床的成药剂型是否也具有抗氧自由基(羟自由基·OH和超氧阴离子自由基O-2·)作用,并且不同剂型之间是否有差异.用邻二氮菲-Fe2+氧化法测定·OH,用改进的邻苯三酚自氧化法测定O-2·.结果表明,3种剂型生脉散均有清除·OH和O-2·的能力,与对照管比较有高度显著性差异(P<0.01),各剂型之间无显著性差异(P>0.05).

关 键 词:生脉注射液  生脉饮  生脉胶囊  氧自由基
文章编号:1007-2985(2007)03-0123-03
收稿时间:2007-01-22
修稿时间:2007-01-22

Comparative Study on the Effect on Removing Oxygen Free Radicals with Different Forms of Shengmai Power
YU Qing-gao,WANG Xiao-chun,ZHONG Fei. Comparative Study on the Effect on Removing Oxygen Free Radicals with Different Forms of Shengmai Power[J]. Journal of Jishou University(Natural Science Edition), 2007, 28(3): 123-125
Authors:YU Qing-gao  WANG Xiao-chun  ZHONG Fei
Affiliation:(1.College of Medical,Xiangtan Vocational & Technical College,Xiangtan 411100,Hunan China;2.Xiangya Medical College,Central South University,Changsha 410078,China;3.College of Medical,Jishou University,Jishou 416000,Hunan China)
Abstract:To study whether the three proprietary forms——Shengmai injection,Shengmai drink,Shengmai capsule,which can be directly used in clinic,have  the effect of  resistance on oxygen free radical (hydrogen radical ·OH and superoxide anion  radical   O-2·,whether there are any differences between the three.Mensurate ·OH with the oxidation of phenathroline -Fe2+,mensurate  O-2·  with improved pyrogallol auto-oxidation.Results shows that  all of the three forms of Shengmai power are of the ability of  removing  ·OH  and  O-2·;there are not significant differences between the three (P>0.05),but there are significant differences when compared with comparison tube (P<0.01).  
Keywords:Shengmai injection  Shengmai drink  Shengmai capsule  oxygen free radicals
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