鼻咽癌调强适形放疗与常规放疗比较分析

目的分析比较鼻咽癌患者调强放疗与常规放疗的优势.方法 70例鼻咽癌患者随机分为两组,调强放疗组(IMRT)35例,常规放疗组(CRT)35例.IMRT组靶区为鼻咽肿瘤、咽旁间隙和颈部淋巴区,放射剂量DT 70 Gy;CRT组采用面颈联合野加颈部切线野照射,原发灶根治量为DT 70~72 Gy,颈部预防治疗量DT 50 Gy.结果 IMRT组和CRT组总有效率分别为94.3%和85.7%,口腔黏膜反应Ⅳ级两组分别为0例和2例,两组比较差异具有统计学意义(P0.05).结论鼻咽癌调强放疗比常规放疗有明显优势.

Analyzing and Comparing of IMRT and Conventional Radiotherapy on NPC

Objective To analyze and compare the advantages of IMRT and conventional radiotherapy of NPC patients. Method 70 cases with NPC are divide into two groups: 35 cases in IMRT group and 35 cases in conventional radiotherapy ( CRT) . To the IMRT group,the targets are neoplasms,parapharyngeal space,cervical lymph node areas and DT 70 Gy;To the CRT group,the methods are face-neck joint field plus neck tangential field irradiation,with the treatment amount of primary tumor cure being DT 70~72 Gy and the treatment amount of prevention and treatment of cervical area being DT 50 Gy. Results The total effects of the IMRT group and the CRT group were 94. 3% and 85. 7%,respectively;the oral mucosa reactions with gradeⅣwere no case and two cases,respectively. There was a significant difference between the two groups (P<0. 05). Conclusion The IMRT has an obvious advantage than the conventional radiotherapy of NPC patients.