| 氯化汞对小白鼠卵巢损伤的显微镜及超微结构研究 |
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| 引用本文： | 李荔,田卫东,等.氯化汞对小白鼠卵巢损伤的显微镜及超微结构研究[J].西北师范大学学报,2001,37(2):56-60. |
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| 作者姓名： | 李荔 田卫东 |
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| 作者单位： | [1]西北师范大学生命科学学院，甘肃兰州730070 [2]甘肃省卫 |
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| 基金项目： | 甘肃省自然科学基金资助项目(ZR-96-022) |
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| 摘 要： | 对氯化汞染毒小白鼠卵巢进行了显微和超微结构研究。结果表明，氯化汞对小白鼠卵巢发育有明显的毒性作用，主要表现出卵巢内发育的卵泡（原始卵泡、生长卵泡、成熟卵泡）数量随剂量的增高依次性减少，而闭锁卵泡的数量则相反，为依次性增高。超微结构显示，从中剂量组开始，卵照相结构表现出病理学变化，主要表现为卵细胞核膜皱缩，染色质凝聚，胞质内线粒体肿胀、变形，外膜和内嵴受损，次级溶酶体及残余小体增多等现象。
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| 关 键 词： | 氯化汞 卵巢损伤 毒性作用 超微结构 卵细胞核膜皱缩 染色质凝聚 小鼠 |
| 文章编号： | 1001-988Ⅹ(2001)02-0056-05 |
| 修稿时间： | 2000年9月7日 |
Study on microstructure
and ultrastructure of overy in the mouse treated with mercuric chloride |
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| LI Li ,LIANG Gui xia ,SI Ke yuan ,TIAN Wei dong.Study on microstructure
and ultrastructure of overy in the mouse treated with mercuric chloride[J].Journal of Northwest Normal University Natural Science (Bimonthly),2001,37(2):56-60. |
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| Authors: | LI Li LIANG Gui xia SI Ke yuan TIAN Wei dong |
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| Institution: | LI Li 1,LIANG Gui xia 1,SI Ke yuan 1,TIAN Wei dong 2 |
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| Abstract: | Microstructure shows that mercuric chloride has the apparent toxic effect on the development of overy in the mouse.The amount of the primary follicle developing follicle and matured follicle in the overy is decreasing with the increasing of exposure dose.The ultrastructure of overy shows the typical pathological symptoms,which are nuclear membrane flodding,chromsome condensing,mitochondrion swelling,deforming and destroying in outer membrane and cristae,the secondary lysosome increasing. |
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| Keywords: | mercuric chloride destroying in overy toxic effect ultrastructure |
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