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| 微波辐射一锅法合成N-(4-芳基噻唑-2-基)-腙类化合物 | |
| 引用本文： | 李记太,张冬暖,刘卉闵,宋亚丽.微波辐射一锅法合成N-(4-芳基噻唑-2-基)-腙类化合物[J].河北大学学报(自然科学版),2012,32(3):261-264,290. |
| 作者姓名： | 李记太 张冬暖 刘卉闵 宋亚丽 |
| 作者单位： | 1. 河北大学化学与环境科学学院,河北保定,071002 2. 河北大学化学与环境科学学院,河北保定071002;河北农业大学理学院,河北保定071001 3. 河北农业大学理学院,河北保定,071001 4. 河北大学药学院,河北保定,071002 |
| 基金项目： | 河北省教育厅计划项目，保定市科技研究与发展指导计划项目 |
| 摘 要： | 在微波辐射下,以异丙醇作溶剂,以醛(或酮)、氨基硫脲和溴代苯乙酮进行一锅3组分反应,探讨了溶剂和微波功率对反应的影响,确定了最佳反应条件,并合成了一系列N-(4-芳基噻唑-2-基)-腙类化合物,反应时间5～10min,产率86%～95%. |
| 关 键 词： | 微波辐射 一锅合成法 N-(4-芳基噻唑-2-基)-腙 缩合反应 |
Microwave-assisted efficient one-pot synthesis of N- (4-arylthiazol-2-yl) hydrazones |
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| LI Ji-tai , ZHANG Dong-nuan , LIU Hui-min , SONG Ya-li.Microwave-assisted efficient one-pot synthesis of N- (4-arylthiazol-2-yl) hydrazones[J].Journal of Hebei University (Natural Science Edition),2012,32(3):261-264,290. | |
| Authors: | LI Ji-tai ZHANG Dong-nuan LIU Hui-min SONG Ya-li |
| Institution: | 1.College of Chemistry and Environmental Science,Hebei University,Baoding 071002,China; 2.College of Science,Agricultural University of Hebei,Baoding 071001,China; 3.College of Pharmaceutical Science,Hebei University,Baoding 071002,China) |
| Abstract: | A highly efficient and facile one-pot three-component synthesis of N-(4-arylthiazol-2-yl) hydrazones was carried out under microwave irradiation.The effects of solvent and microwave power were investigated.The process proceeded smoothly to give title compounds in 86%-95% yields within 5-10 min. |
| Keywords: | microwave irradiation one-pot synthesis N-(4-arylthiazol-2-yl) hydrazones condensation |
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