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Relationship between the pentose phosphate shunt and methemoglobin reductase activity in human erythrocytes: Effect of aging on methemoglobin reductase activity
Authors:C Ioppolo  D L Currell  L Civalleri  E Antonini
Institution:(1) Institute of Chemistry, Faculty of Medicine, University of Rome, C.N.R. Center of Molecular Biology, Roma, Italy;(2) Present address: Dept. of Chemistry, California State University, 90032 Los Angeles, California, USA
Abstract:Summary The increase in methemoglobin reductase activity in human erythrocytes upon incubation with inosine, phosphate, pyruvate occurs only in the presence of methylene blue. No difference in activity of the methemoglobin reductases was observed between enzyme extracts of fresh cells and aged cells.
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