DNA and its precursors might interact with the food preservatives,sodium sulphite and sodium benzoate |
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| Authors: | G D E Njagi H N B Gopalan |
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| Institution: | (1) Department of Botany, Kenyatta University College, P. O. Box 43844, Nairobi, (Kenya);(2) Present address: Institute of Animal Genetics, University of Edinburgh, Edinburgh, Scotland;(3) Department of Botany, University of Nairobi, P.O. Box 30197, Nairobi, Kenya |
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| Abstract: | Summary The interaction of sodium sulphite and sodium benzoate with nucleosides and DNA has been studied in vitro. Reduction in UV-absorbance was consistently noticed. However, no new products result from such interaction. It is likely that our previous observations of the effects of the 2 food preservatives on DNA synthesis and mitotis inVicia faba root meristems is not due to direct action of the chemicals at the level of genetic material.We are grateful to Professor P.A. Robbins and Dr. A.S. Herbin of the Department of Chemistry, University of Nairobi for their help. |
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