The involvement of RNA in ribosome function |
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Authors: | Moore Peter B Steitz Thomas A |
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Affiliation: | Department of Molecular Biophysics and Biochemistry, Yale University, PO Box 208107, New Haven, Connecticut 06520-8107, USA. peter.moore@yale.edu |
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Abstract: | The ribosome is a particle made of RNA and protein that is found in abundance in all cells that are actively making protein. It catalyses the messenger RNA-directed synthesis of proteins. Recent structural work has demonstrated a profound involvement of the ribosome's RNA component in all aspects of its function, supporting the hypothesis that proteins were added to the ribosome late in its evolution. |
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