Inhibitory tripeptide,Lys-Phe-Tyr,as a fragment of physalaemin |
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Authors: | H Takeuchi T Morimasa M Matsumoto |
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Institution: | (1) Institute for Neurobiology, Okayama University Medical School, 2-5-1 Shikata-cho, Okayama, Japan |
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Abstract: | Summary Several peptides were separated from -chymotrypsin-treated physalaemin by high voltage paper electrophoresis, and inhibition of the excitability of a molluscan giant neurone (tonically autoactive neurone) by the tripeptide, Lys-Phe-Tyr, was demonstrated.We thank Dr Sadaaki Iwanaga of Osaka University and Dr Atsuo Inoue of Daiichi Pharmaceutical CO for their helpful advice and the donation of the tripeptide (Lys-Phe-Tyr). |
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