Effect of lanthanons on substrate-induced difference spectra in rat liver microsomes |
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Authors: | P Arvela O Grajewski B v Lehmann E Oberdisse |
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Institution: | (1) Department of Pharmacology, Free University of Berlin, Thielallee 69/73, D-1000 Berlin 33, Berlin West |
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Abstract: | Summary Intravenously administered light lanthanons change spectral interactions in rat liver not only by decreasing the concentration of cytochrome P-450, but they also cause a qualitative change in the cytochrome P-450 molecule or its microenvironment.P. Arvela is a fellow of the Alexander-von-Humboldt-Stiftung. |
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