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Rosette formation by human T and B lymphocytes in the presence of adrenergic and cholinergic drugs.
Authors:G G Ferreira  H K Brascher  M Q Javierre  W A Sassine  A O Lima
Abstract:It was shown that adrenergic drugs, which increase the intracellular levels of cAMP, inhibit the rosette formation by T-lymphocytes, but stimulate the rosettes produced by B-lymphocytes. Cholinergic drugs, which increase the levels of cGMP, on the contrary, stimulate the formation of rosettes by T-lymphocytes but inhibit those produced by B-lymphocytes.
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