Renale Enzymausscheidung im anaphylaktoiden Schock nach Verabreichung vonge-Aminocapronsäure

Summary In rats pretreated with-amino-caproic acid urinary leucine aminopeptidase (LAP) and alkaline phosphatase (AP) activities were determined following anaphylactoid shock (Compound 48/80). Both enzymatic activities were found to be increased, the increase measuring 110% in AP and 80% in LAP. The values obtained were much lower than in rats without antifibrinolytic treatment. The significance of this finding is briefly discussed.