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Position of the Y-chromosome at somatic metaphase in patients with chronic myelogenous leukemia (CML)
Authors:R S Verma  S Thomas  M Coleman  R T Silver  H Dosik
Institution:(1) Interfaith Medical Center, SUNY Downstate Medical Center, 11238 Brooklyn, New York, USA;(2) Cornell Medical Center, The New York Hospital, New York, New York, USA
Abstract:Summary A random distribution of the Y-chromosome at somatic metaphase was found in 50 patients with Ph' positive chronic myelogenous leukemia (CML). Thus, it is concluded that the lsquopositiversquo of the Y-chromosome at somatic metaphase does not appear to influence the loss from bone marrow cells.
Keywords:Chronic myelogenous leukemia (CML)  Ph'-chromosome  Y-chromosome
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