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The metabolic fate of [35S]-diallyl disulphide in mice
Authors:C K Pushpendran  T P A Devasagayam  G J Chintalwar  A Banerji  J Eapen
Institution:(1) Biology Group, Bhabha Atomic Research Centre, 400085 Bombay, (India)
Abstract:Summary Diallyl disulphide (DADS) is a major constituent of garlic oil. Uptake of 35S]-labelled diallyl disulphide by mouse liver is highest at 90 min after treatment. 2h after treatment with 35S]-DADS, 70% of the radioactivity is present in the liver cytosol of which 80% is metabolized to sulphate.
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