| 固本清肺贴膏对豚鼠过敏性哮喘模型的影响 |
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| 引用本文： | 李显华,宋达夫,甘雨,杜佳林,乔世举,周淑梅,顾晓颖.固本清肺贴膏对豚鼠过敏性哮喘模型的影响[J].实验动物科学,2010,27(1):25-26. |
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| 作者姓名： | 李显华 宋达夫 甘雨 杜佳林 乔世举 周淑梅 顾晓颖 |
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| 作者单位： | 辽宁省中医药研究院,沈阳,110034 |
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| 基金项目： | 国家"十一五"科技支撑计划项目 |
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| 摘 要： | 目的通过建立豚鼠过敏性哮喘模型,观察固本清肺贴膏对豚鼠哮喘模型的平喘、抗炎作用。方法采用腹腔注射10%卵蛋白生理盐水致敏,14d后用1%卵蛋白生理盐水激发3次,建立豚鼠过敏性哮喘模型,观察固本清肺贴膏对哮喘豚鼠的引喘潜伏期及支气管肺泡灌洗液中白细胞总数的影响。结果固本清肺贴膏能延长哮喘豚鼠引喘潜伏期、减少哮喘豚鼠支气管肺泡灌洗液中白细胞总数。结论固本清肺贴膏对豚鼠过敏性哮喘模型具有平喘和抗炎作用。
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| 关 键 词： | 固本清肺贴膏 豚鼠 过敏性哮喘 |
| 收稿时间： | 2010-02-28 |
Effect of Guben Qingfei Tiegao on Guinea Pig Model of Allergic Asthma |
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| LI Xian-hua,SONG Da-fu,GAN Yu,DU Jia-lin,QIAO Shi-ju,ZHOU Shu-mei,GU Xiao-ying.Effect of Guben Qingfei Tiegao on Guinea Pig Model of Allergic Asthma[J].Shiyan Dongwu Kexue,2010,27(1):25-26. |
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| Authors: | LI Xian-hua SONG Da-fu GAN Yu DU Jia-lin QIAO Shi-ju ZHOU Shu-mei GU Xiao-ying |
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| Institution: | LI Xian-hua,SONG Da-fu,GAN Yu,DU Jia-lin,QIAO Shi-ju ZHOU Shu-mei,GU Xiao-ying(Traditional Chinese Medicine Research Institute in Liaoning Province,Shen Yang 110034,China) |
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| Abstract: | Objective By using the guinea pig model of allergic asthma, to determine the effects of Guben Qingfei Tiegao on relieving asthma and anti-inflammatory.Methods The guinea pigs were allergized by intraperitoneal injection with 10% ovalbumin normal saline solution. Fourteen days later, they were stimulated with 1% ovalbumin normal saline 3 times. After treating with the Guben Qingfei Tiegao, the latency period of asthma and the amount of WBC in bronchovesicular irrigating solution were detected.Results Guben Q... |
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| Keywords: | Guben Qingfei Tiegao Guinea pig Allergic asthma Animal model |
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