Evidence for the possible function of the fluorescent granular perithelial cells in brain as scavengers of high-molecular-weight waste products |
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Authors: | M Mato S Ookawara M Sugamata E Aikawa |
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Institution: | (1) Department of Anatomy, Jichi Medical School, Minamikawachi, 329-04 Tochigi, Japan;(2) Department of Anatomy, Medical College of Miyazaki, 889-16 Miyazaki, (Japan) |
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Abstract: | Summary The fluorescent granular perithelium (FGP) of rats and humans under experimental and pathological conditions was examined with the electron microscope. The FGP incorporated high molecular-weight protein (ferritin) and carbon particles administered intraventricularly. In a case of spontaneous cerebral hemorrhage, the FGP was found to contain lipoidal products and minute fragmented cell debris. The FGP in a patient with lipidosis contained pale inclusion bodies. In aged individuals, the inclusion bodies formed irregular larger aggregates. |
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