Effect of tranexamic acid on progress of experimental tumours and on DNA-synthesis |
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| Authors: | B. Åstedt C. Tropé |
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| Affiliation: | (1) Research Laboratory of the Department of Obstetrics and Gynecology, University Hospital, S-221 85 Lund, (Sweden);(2) Department of Oncology, University Hospital, S-221 85 Lund, (Sweden) |
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| Abstract: | Summary The fibrinolytic inhibitor tranexamic acid affects certain experimental tumours; it prolongs survival (Lewis lung adenocarcinoma), decreases tumour weight (C3H breast carcinoma), and inhibits ascitic production (AH 130 rat hepatoma). However, it does not significantly influence DNA-synthesis in cell suspensions prepared from the same tumours.Acknowledgment. This study was supported by grants from Malmö Allmänna Sjukhus and the Swedish Medical Research Council (B79-17X-04523-05B). |
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