Somatostatin and 3-oxy-methyl-D-glucose (3-OMG) uptake in isolated chicken intestinal epithelial cells |
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Authors: | M. Abalde C. Taboada P. Fernández |
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Affiliation: | (1) Departamento de Fisiologia Animal, Facultad de Farmacia, Universidad de Santiago, Santiago de Compostela, (Spain) |
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Abstract: | Summary The direct effect of somatostatin on the absorption of 3-oxymethylglucose in epithelial cells isolated from the small intestine of chicken was studied. The presence of somatostatin in the incubation medium at concentrations of 3.5×10–8 M and 7×10–8 M produced significant dose-dependent increases in the accumulation of sugar in the enterocytes. This effect might be due to an increase in the cell membrane permeability caused by hormone action. |
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