Organisation of the genes coding for 5S RNA in the Chinese hamster.

Hybridisation of iodinated mouse 5S RNA with Chinese hamster DNA fractionated on a CsCl gradient, identifies two separate DNA components that hybridise with the labelled probe. One component is slightly, and one considerably heavier than the main band DNA. This suggests that the gene coding for 5S RNA in the Chinese hamster may constitute two distinct populations differing in G + C content of their adjacent spacer regions.