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Dissolution of gallstones in hamsters by 3-hydroxy-3-methylglutaric acid
Authors:D Kritchevsky  J A Story  D M Klurfeld
Institution:(1) The Wistar Institute of Anatomy and Biology, 36th Street at Spruce, 19104 Philadelphia, PA, USA;(2) Present address: Dept. Foods and Nutrition, Purdue University, 47907 W. Lafayette, Indiana
Abstract:Summary Addition of 0.05–0.20% of 3-hydroxy-3-methylglutaric acid to a lithogenic hamster diet resulted in a marked reduction in the incidence of gallstones in hamsters.Supported, in part, by grants HL-03299, AG-00076 and T32 CA-09171 and a Research Career Award, HL-0734 from the National Institutes of Health.
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