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Method for long term delivery of soluble agents to the chick chorioallantoic membrane
Authors:Ph. R. Waggoner  Nancy J. Philp
Affiliation:(1) Department of Anatomy, School of Medicine, Wayne State University, 540 E. Canfield, 48201 Detroit, Mi., USA;(2) Present address: Department of Anatomy (R-124), University of Miami, School of Medicine, P.O. Box 016960, 33101 Miami, Florida
Abstract:Summary Osmotic minipumps were used to administer thyroxine to the chick embryo. This technique proved to be a convenient and efficacious method for the delivery of soluble agents to the chorioallantoic membrane. The thyroxine induced the precocious appearance of extensive cell sloughing by the corneal epithelium.
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