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Multi-phaseted problems of TDP-43 in selective neuronal vulnerability in ALS
Authors:Asakawa  Kazuhide  Handa  Hiroshi  Kawakami  Koichi
Institution:1.Department of Chemical Biology, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-8402, Japan
;2.Division of Molecular and Developmental Biology, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka, 411-8540, Japan
;3.Department of Genetics, Graduate University for Advanced Studies (SOKENDAI), 1111 Yata, Mishima, Shizuoka, 411-8540, Japan
;
Abstract:Cellular and Molecular Life Sciences - Transactive response DNA-binding protein 43 kDa (TDP-43) encoded by the TARDBP gene is an evolutionarily conserved heterogeneous nuclear...
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