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Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation |
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| Authors: | Prasad Parash Ghosh Sampurna Roy Sib Sankar |
| Affiliation: | 1.Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata, 700032, India ;2.Academy of Scientific and Innovative Research, CSIR-Indian Institute of Chemical Biology Campus, 4 Raja S. C. Mullick Road, Kolkata, 700032, India ; |
| Abstract: | Cellular and Molecular Life Sciences - Glutamine is essential for maintaining the TCA cycle in cancer cells yet they undergo glutamine starvation in the core of tumors. Cancer stem cells (CSCs),... |
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